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Stage 6: Diseases and Disorders

Inflammation, infection, cancer, diabetes and other common conditions.

Introduction to Disease

What disease means, how conditions develop, and the difference between acute and chronic.

  • How Disease Develops: From Cause to Consequence (coming soon)
  • Acute vs Chronic: Two Different Shapes of Disease (coming soon)
  • The Natural History of Disease: Why So Much Happens Before You Notice (coming soon)

Infection and Immunity

Bacteria, viruses, antibiotics, resistance and how vaccines protect populations.

  • Infection: When Something Else Gets Inside (coming soon)
  • Antibiotic Resistance: How Bacteria Stop Responding to Treatment (coming soon)
  • Vaccines: Teaching the Immune Response in Advance (coming soon)
  • Sepsis: When Infection Causes Life-Threatening Organ Dysfunction (coming soon)
  • Pneumonia: Infection in the Lungs (coming soon)
  • Urinary Tract Infection and Pyelonephritis: Infection from Bladder to Kidney (coming soon)
  • Meningitis and Encephalitis: Infection Around or Within the Brain (coming soon)
  • Infectious Gastroenteritis: Infection of the Stomach and Bowel (coming soon)
  • Tuberculosis: A Persistent Bacterial Infection (coming soon)
  • HIV: How a Virus Weakens Immune Defence (coming soon)
  • Influenza and COVID-19: Two Viral Respiratory Diseases (coming soon)
  • Pelvic Inflammatory Disease: Infection of the Upper Reproductive Tract (coming soon)

Inflammation and Autoimmune Disease

When the immune system attacks the body — and what inflammation really is.

  • Inflammation: The Body's Repair Response, and What Happens When It Persists (coming soon)
  • Autoimmune Disease: When Defence Turns Inward (coming soon)
  • Rheumatoid Arthritis: Autoimmune Inflammation of the Joints (coming soon)
  • Systemic Lupus Erythematosus: An Autoimmune Disease with Many Patterns (coming soon)
  • Crohn's Disease and Ulcerative Colitis: Two Forms of Inflammatory Bowel Disease (coming soon)
  • Coeliac Disease: An Immune Reaction to Gluten (coming soon)
  • Multiple Sclerosis: When the Immune System Attacks Nerve Insulation (coming soon)

Cancer

What cancer is, how it grows, spreads and is treated — in plain English.

  • Cancer Basics: What Actually Goes Wrong at the Cellular Level (coming soon)
  • Breast Cancer: One Name, Several Biological Subtypes (coming soon)
  • Lung Cancer: Different Cancers Arising in the Lungs (coming soon)
  • Bowel Cancer: Cancer of the Colon and Rectum (coming soon)
  • Prostate Cancer: Disease Ranging from Slow-Growing to Aggressive (coming soon)
  • Skin Cancer: Melanoma and Non-Melanoma Cancers (coming soon)
  • Blood Cancers: Leukaemia, Lymphoma and Myeloma (coming soon)

Long-Term Conditions

Diabetes, high blood pressure, asthma, kidney disease, mental health and more.

  • Diabetes and Metabolic Disease: Why One Ongoing Disturbance Affects So Much (coming soon)
  • High Blood Pressure: The Long-Term Condition That Rarely Announces Itself (coming soon)
  • Asthma and COPD: Two Different Ways the Airways Can Narrow (coming soon)
  • Chronic Kidney Disease: Why So Much Function Can Be Lost Before It Shows (coming soon)
  • Chronic Pain: When Pain Itself Becomes the Condition (coming soon)
  • Mental Health Conditions: Genuine Illness, Not a Character Trait (coming soon)
  • Monitoring Long-Term Conditions: Why the Same Pattern Keeps Appearing (coming soon)

Rare and Complex Conditions

Genetic conditions, multi-system disorders and how rare disease medicine works.

  • What Makes a Condition Rare, and Why That Changes Everything About Finding It (coming soon)
  • Genetic Conditions in Plain English: Having a Gene Change Is Not the Same as Having the Condition (coming soon)
  • Multi-System Disorders: When One Underlying Process Explains Many Different Symptoms (coming soon)

Cardiovascular and Circulatory Diseases

  • Coronary Heart Disease and Angina: Reduced Blood Flow to Heart Muscle (coming soon)
  • Heart Attack: Sudden Injury to Heart Muscle (coming soon)
  • Heart Failure: When the Heart Cannot Pump Enough (coming soon)
  • Atrial Fibrillation: An Irregular Heart Rhythm (coming soon)
  • Stroke and Transient Ischaemic Attack: When Brain Blood Flow Is Disrupted (coming soon)

Respiratory Diseases

  • Bronchiectasis: Permanently Widened and Damaged Airways (coming soon)
  • Pulmonary Fibrosis: Scarring of the Lungs (coming soon)
  • Pneumothorax: Air Around the Lung Causing Partial or Complete Collapse (coming soon)
  • Obstructive Sleep Apnoea: Repeated Airway Closure During Sleep (coming soon)

Digestive and Liver Diseases

  • Acid-Related Disorders: Gastro-Oesophageal Reflux Disease and Peptic Ulcer Disease (coming soon)
  • Irritable Bowel Syndrome (coming soon)
  • Diverticular Disease and Diverticulitis (coming soon)
  • Chronic Liver Disease and Cirrhosis (coming soon)

Neurological Disorders

  • Epilepsy (coming soon)
  • Migraine (coming soon)
  • Parkinson's Disease (coming soon)
  • Dementia (coming soon)

Musculoskeletal and Bone Disorders

  • Osteoarthritis (coming soon)
  • Osteoporosis (coming soon)
  • Gout (coming soon)
  • Fibromyalgia (coming soon)

Endocrine and Hormonal Disorders

  • Hypothyroidism (coming soon)
  • Hyperthyroidism (coming soon)
  • Addison's Disease (coming soon)
  • Cushing's Syndrome (coming soon)

Kidney and Urinary Disorders

  • Acute Kidney Injury (coming soon)
  • Kidney Stones (coming soon)
  • Glomerulonephritis and Nephrotic Syndrome (coming soon)

Blood and Clotting Disorders

  • Anaemia (coming soon)
  • Sickle Cell Disease and Thalassaemia (coming soon)
  • Venous Thromboembolism: Deep Vein Thrombosis and Pulmonary Embolism (coming soon)
  • Bleeding and Clotting Disorders: Haemophilia and Von Willebrand Disease (coming soon)

Skin Disorders

  • Atopic Eczema: A Relapsing Inflammatory Skin Disorder (coming soon)
  • Psoriasis: Immune-Mediated Skin Disease (coming soon)
  • Acne Vulgaris: Inflammation of Hair Follicles and Sebaceous Glands (coming soon)

Mental Health Disorders

  • Depression: A Disorder Affecting Mood, Thought and Function (coming soon)
  • Generalised Anxiety Disorder: Persistent Anxiety Beyond Immediate Threat (coming soon)
  • Bipolar Disorder: Episodes of Depression and Abnormally Elevated Mood (coming soon)
  • Schizophrenia and Other Psychotic Disorders: Changes in Perception, Thought and Reality Testing (coming soon)

Reproductive System Disorders

  • Endometriosis: Tissue Similar to the Womb Lining Growing Elsewhere (coming soon)
  • Uterine Fibroids: Non-Cancerous Growths of the Womb (coming soon)
  • Polycystic Ovary Syndrome: A Hormonal and Metabolic Disorder (coming soon)
  • Benign Prostatic Enlargement: Non-Cancerous Growth of the Prostate (coming soon)